Advancements in Bioidentical Hormone Replacement Therapy


Bioidentical Hormone Replacement Therapy (BHRT) has garnered significant attention in recent research, revolutionizing hormone therapy with its personalized and precise approach1. This article delves into the latest news and scientific developments surrounding BHRT, shedding light on its numerous benefits for individuals seeking hormone balance.

The Bioidentical Advantage

Bioidentical hormones are structurally identical to those naturally produced by the body, setting BHRT apart from synthetic hormone replacements2. This inherent similarity allows for a more seamless integration into the body’s hormonal pathways, reducing the risk of adverse effects and optimizing therapeutic outcomes.

Tailored Precision in Treatment

Recent advancements in BHRT underscore the importance of individualized treatment plans. Clinicians now have access to advanced diagnostic tools, allowing them to precisely assess a patient’s hormonal profile3. This tailored approach ensures that BHRT addresses specific deficiencies, promoting optimal balance without the one-size-fits-all limitations of conventional hormone therapies.

Mitigating Menopausal Symptoms

BHRT has proven particularly effective in alleviating menopausal symptoms. Recent studies4 indicate that personalized BHRT formulations can significantly reduce hot flashes, night sweats, and mood swings associated with menopause. This individualized approach tailors treatment to a woman’s unique hormonal needs, providing relief with fewer side effects.

Cardiometabolic Health Benefits

Emerging research points towards the potential cardiometabolic benefits of BHRT. Studies5 suggest that BHRT may contribute to improved cardiovascular health by positively impacting lipid profiles and reducing the risk of metabolic disorders associated with hormonal imbalances. Further exploration in this area may unveil additional avenues for utilizing BHRT in preventive medicine.

Cognitive Well-being and BHRT

Recent investigations into the cognitive effects of BHRT have shown promise in supporting brain health. Preliminary findings6 suggest that BHRT may have a positive impact on cognitive function, potentially reducing the risk of cognitive decline in aging individuals. Ongoing research seeks to elucidate the mechanisms behind these cognitive benefits.

Cancer Risk and BHRT

The association between hormone replacement therapy and cancer risk has long been a topic of concern. However, recent studies7 exploring BHRT have provided encouraging insights. Current evidence suggests that BHRT, when appropriately prescribed and monitored, may have a favorable safety profile, minimizing the risk of certain cancers associated with traditional hormone replacement therapies.


The latest developments in Bioidentical Hormone Replacement Therapy underscore its potential as a transformative approach to hormone balance. From tailored precision in treatment to the mitigation of menopausal symptoms and potential cardiometabolic and cognitive benefits, BHRT is emerging as a multifaceted solution. As ongoing research continues to unravel the intricacies of BHRT, it is becoming increasingly evident that personalized and bioidentical approaches hold the key to unlocking the full spectrum of benefits for those seeking hormone balance and overall well-being.


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Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


How Hormone Therapy May Help Migraine Headaches

Testosterone deficiency and cardiovascular disease in men may be linked. In the United States, heart disease is the top cause of death in men. Heart disease accounts for 1 in 4 deaths for men. However, for men who do have a testosterone deficiency, testosterone therapy may be one safe and effective method of protecting against cardiovascular issues.

Testosterone deficiency in male patients lead to many unpleasant side effects. But physicians across the nation are seeing a correlation between testosterone deficiency and increase risk of serious disease or even death. As studies evolve on the topic of low testosterone and mortality rates, physicians are seeking ways to help their patients achieve more positive outcomes and live longer. Physician hormone replacement therapy (HRT) training helps physicians understand how to dose their male patients to meet their unique needs.

Causes of Testosterone Deficiency

There are many causes of testosterone deficiency in men. As men grow older, testosterone production natural declines. Other causes of decrease in testosterone production include issues such as testicular failure, trauma, and chronic illness.

In a recent study, it was concluded that there is no evidence that testosterone therapy is not related to an increased risk in cardiovascular problems. But there is ample evidence that testosterone therapy does not increase risk.

Many studies support testosterone replacement therapy as a cardiovascular benefit. This is noteworthy because low levels of testosterone are associated with increased risk of cardiovascular disease and death. Men who receive testosterone replacement therapy with a higher concentration see greater improvement in cardiac risk and mortality rates.

Testosterone replacement therapy has additional benefits such as improvement in myocardial ischemia, exercise capacity, and glucose levels.

Testosterone’s Effects on the Male Cardiovascular System

Testosterone has a significant effect on a male’s cardiovascular system. As men age, typically after age 40, testosterone levels will begin to decrease. This decrease is linked to an increase in mortality and cardiovascular risks.

Low testosterone levels put men at a greater risk of developing type 2 diabetes, coronary artery disease (CAD), and metabolic syndrome. Reduced testosterone levels further complicate the prognosis for men with congestive heart failure (CHF) and can lead to higher mortality rates.

Testosterone replacement therapy can improve many of the cardiovascular diseases that older men face. Testosterone therapy is also linked to reduced mortality in men who were previously testosterone deficient.

Testosterone Deficiency and Coronary Artery Disease

Testosterone deficiency may be associated with more severe cases of coronary artery disease (CAD).

A review conducted in 2013 provided supporting evidence that men with lower serum testosterone levels are more likely to develop coronary artery disease. This study also evaluated the severity of CAD in association with testosterone levels in the blood. These studies found that coronary artery disease was more severe in men who reported with lower testosterone levels.

While the sample size on these studies were small, they show promising correlation between higher serum testosterone levels and decreased severity of CAD.

Testosterone Deficiency and Congestive Heart Failure

Testosterone deficiency is found in many cases of congestive heart failure.

As congestive heart failure continues to be studies, there is evidence to suggest it is more than just failure of the heart. Congestive heart failure may involve other pathways such as the endocrine and muscular systems. In a study of 208 men with congestive heart failure, low serum testosterone levels were found in all classes. These reduced testosterone levels are also associated with more serious patient outcomes and increased risk of death.

Testosterone Deficiency and Metabolic Syndrome

Testosterone deficiency has been shown to be linked to metabolic syndrome (MetS). In an observation study, it was found that there is a relationship between total testosterone, free testosterone, sex hormone binding globulin (SHBG) and metabolic syndrome.

The relationship varied across different aspects of MetS but were stronger for abdominal obesity, high triglycerides, and high blood sugar.

Many studies have established that men with type 2 diabetes have lower levels of testosterone compared to men without diabetes. Studies also indicate that men are most testosterone deficient are also at increased risk of metabolic syndrome and type 2 diabetes.

2023 Research Studies on Low Testosterone & Cardiovascular Disease

There were several new research studies conducted in 2023 investigating the relationship between testosterone deficiency and cardiovascular disease (CVD) in men.

In 2023 a Cleveland Clinic-Led Trial entitled Testosterone Replacement Therapy and Incident Cardiovascular Events in Men was published in the New England Journal of Medicine1. This large-scale, randomized, double-blind, placebo-controlled trial assessed over 5,000 men with low testosterone and pre-existing or high-risk CVD. They found that testosterone replacement therapy did not increase the risk of major adverse cardiovascular events compared to placebo. This study provided important reassurance regarding the cardiovascular safety of testosterone replacement therapy in this population.

Also in 2023, the Danish Registry Study published in the JAMA Network Open2 analyzed data from over 120,000 men with type 2 diabetes. They found that lower testosterone levels were associated with an increased risk of myocardial infarction (heart attack), highlighting the potential link between testosterone deficiency and heart health in this population.

Additionally, a 2023 review of various clinical trials and observational studies published in the Sexual Medicine Review summarized the evidence on the relationship between testosterone deficiency and CVD. The authors concluded that there is compelling evidence for a detrimental effect of low testosterone on vascular health and increased risk of CVD in men with hypogonadism.

While these are just a few examples of recent studies on testosterone and CVD – and research in this area is ongoing – it is increasingly evident that low testosterone levels in men present a significant risk factor for the development of cardiovascular disease.

As a SottoPelle Method HRT trained physician you will be better able to assess your patients’ individual CVD risk factors and evaluate the potential benefits of testosterone replacement therapy – based on each patient’s specific circumstances to ensure they receive the appropriate care.

Physician Training for Treating Testosterone Deficiency

Treating testosterone deficiency may not solve or prevent every disease. However, studies support the evidence that testosterone replacement can help to reduce risks of metabolic syndrome, congestive heart failure, and diabetes.

The SottoPelle® Method places an emphasis on treating patients and their individual needs. SottoPelle® Certified Providers are taught how to individually customize dosages for their patients.

Bio-identical hormones, such as pellets used in the SottoPelle® Method, replicate the structure of hormones naturally created by the body. Bio-identical hormones are more effective than pills, patches, or creams. They are also safer for patients, without side effects caused by synthetic hormone replacement therapy methods.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


How Hormone Therapy May Help Migraine Headaches

The relationship between hormones, particularly hormonal decline or deficiency, and migraine headaches is a complex and multifaceted area of study within the fields of neurology and endocrinology. Migraines, which are severe headaches often accompanied by other symptoms like nausea and sensitivity to light, affect a substantial portion of the population, and their connection to hormonal fluctuations has been widely investigated.

According to the Migraine Research Foundation, migraine is the 3rd most prevalent and 6th most disabling disease in the world.1 A World Health Organization report in 2018, an estimated 1 billion people worldwide suffer from migraines, making it one of the most common neurological disorders.

And in 2023 the American Migraine Foundation estimated that 39 million people in the United States, or 15.1% of the adult population, experience migraine headaches. Also in 2023, The Migraine Research Foundation emphasized that migraines can significantly impact quality of life, causing missed workdays, reduced productivity, and social limitations.

In this article the hormone replacement experts at SottoPelle Method explore the connections between hormones and migraines.

Who Gets Migraine Headaches

While migraine symptoms can start as early as age 5, they typically present with different triggers compared to adults, according to the American Migraine Foundation. Much more commonly, migraine headaches typically begin in adolescence or early adulthood, with peak prevalence between the ages of 25 and 55, per the National Headache Foundation.

And the prevalence of migraines decreases after 55 years old, but the condition can still persist in older adults. As with any disease or disorder, early diagnosis and treatment are crucial for managing migraines effectively and improving patients’ quality of life.

Migraine headaches are more common in women than men, with a ratio of roughly three to one. In women, fluctuations in estrogen levels, especially during the menstrual cycle, pregnancy, and menopause, are often linked to migraines. For many women, migraines tend to coincide with specific phases of the menstrual cycle, particularly the drop in estrogen levels just before menstruation begins. This has led to the term “menstrual migraines.” Similarly, during perimenopause and menopause, when estrogen levels decline more permanently, some women may experience changes in the frequency and intensity of migraines, as well.

It is commonly accepted that genetics play an important roles in who is predisposed to getting migraines. And environmental influences are also well known to “trigger” migraines. Certain foods, alcohol, perfumes or fragrances, are common migraine triggers – as are stress, lack of sleep, dehydration and other lifestyle issues.

The Hormone / Migraine Connection

However, the precise mechanisms underlying the connection between hormones and migraines are not fully understood. But the fact that there is a correlation between the onset and decline of migraines and hormonal events such as adolescence, menstrual cycles, and menopause, have led researchers to believe that there may be a strong hormonal component involved in migraines.

It is believed that estrogen plays a role in regulating pain perception and modulating neurotransmitters in the brain. So, when estrogen levels fluctuate, it may trigger changes in blood vessels and neurotransmitters, contributing to the onset of migraines.

In men, although the relationship between hormones and migraines is less studied, some evidence suggests that imbalances in testosterone and other hormones could also play a role. Testosterone deficiency, for example, has been implicated in certain types of headaches.

And, various hormonal treatments, including birth control methods as well as hormone replacement therapy (HRT) for women going through menopause, have been shown to affect migraine headache frequency – further indicating that there is a strong hormone / migraine connection.

Treating Migraines with Hormone Therapy

Women have been telling their doctors for many years, that their migraines coincide with their menstrual cycles and that they seem to get worse during perimenopause and menopause. Unfortunately, these concerns often fell on deaf ears because medical research simply wasn’t abundant enough to back them up. The good news is that science is finally catching up.

Hormonal changes in women are a frequent trigger for those susceptible to migraine attacks. This happens when estrogen levels drop during the menstrual cycle and menopause, or when they fluctuate wildly as they do in perimenopause. A review of current literature published in 2014 found that: 1) women were more likely than men to suffer from migraines; 2) that considerable evidence supports an important role for sex hormones, and 3) that women’s migraines tended to be precipitated by drops in estrogen concentrations, and minimizing this decline may prevent these headaches.2 In fact, proper hormone treatment has been found to help reduce the incidence of migraines for women both before and during menopause.3

Another study reported in 2009 showed that maintaining stable estrogen levels in menopausal women with a history of migraines markedly reduced the incidence of these headaches.4 In this and other studies, the use of non-oral, bioidentical forms of estradiol delivery helped achieve maximum results. This was due to the ability of those methods to deliver a steady, consistent dose of hormone.

It’s important to note that these studies also found that synthetic estrogen and oral forms of the hormone can actually worsen migraines. This is because these methods of hormone delivery simply can’t produce stable, dependable hormone levels around the clock, like subdermal BHRT pellets do.

Estradiol Hormone Therapy for Migraines

The best results have been achieved using estradiol under-the-skin (subdermal) pellets,5 which provide steady, 24/7 doses of hormone for months at a time. Early research (1974) by Greenblatt demonstrated that both menstrual and postmenopausal migraine could be controlled with subcutaneous hormone pellets.6 That study concluded that estrogen pellets alleviated all symptoms in the majority of his menopausal patients, and that maintenance of stable estrogen levels would control menopausal migraine.

For years, Dr. Gino Tutera, BHRT pioneer and the founder of SottoPelle® Method, used bioidentical estradiol pellets to treat hormone deficient women of all ages who suffered from migraines. A 90 percent success rate was achieved with this approach. Estrogen levels were restored for these patients within three to seven days and their headaches were either reduced significantly or eliminated.

Migraine Headache Hormone Therapy

Understanding the interplay between hormones and migraines is crucial for developing targeted treatments. Hormone therapies, lifestyle modifications, and other interventions can be combined in a comprehensive treatment plan to manage migraines more effectively, especially in individuals whose headaches are influenced by hormonal fluctuations.

However, due to the complexity of these interactions, personalized approaches by a trained hormone therapy specialist are recommended for a comprehensive assessment and tailored migraine treatment plan.

If you are suffering from migraines and have been unsuccessful in treating them with other methods, the issue may be your hormones.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


How Natural Estrogen Replacement Therapy Treats Osteoporosis

For many women, the decline in estrogen production that occurs due to menopause causes very visible and frustrating side-effects. These can include hot flashes, mood swings, hard-to-lose belly fat, insomnia, and more. But a much more dangerous consequence of menopausal hormone decline remains invisible:  the weakening of a woman’s bones or “osteoporosis”.

Estrogen, while primarily thought of as a “reproductive hormone,” is also essential to maintaining strong, healthy bones. As estrogen levels decline during menopause, the bones lose calcium. This puts a woman at serious risk of one or more broken bones. In fact, a full fifty percent of women over the age 50 will suffer a bone fracture because of osteoporosis!

And, since osteoporosis has no obvious external symptoms, many women do not even realize that they have it until they experience a fracture.

The good news is that osteoporosis can be prevented in women nearing or during menopause, through the use of 100% natural, convenient and safe bioidentical estrogen replacement therapy.

Preventing Osteoporosis with Natural Estrogen Replacement Therapy

To begin with, it is helpful to understand how proper hormone balance protects bones.  One of estrogen’s many functions is to stimulate activity in certain cells – called “osteoblasts” – that produce bone. So, when a woman’s estrogen level drops due to menopause, these osteoblasts no longer produce new bone cells, and the bones become more “hollow” or porous and weaker.

The very first FDA treatment that was approved to prevent osteoporosis was actually estrogen replacement therapy! Subsequently, pharmaceutical companies have jumped on the osteoporosis bandwagon, offering a variety of synthetic drugs and medications to improve bone density. These include bisphosphonates (like Fosamax and Boniva) and anabolic drugs. But, as with any lab-created drug, osteoporosis medicines come with a wide array of side effects.

So, while there are now many new synthetic drugs for osteoporosis, most enlightened medical professionals prefer to treat the underlying cause of osteoporosis – estrogen deficiency – in order preserve bone density and prevent bone fractures in post-menopausal women. But just replacing estrogen with a one-size-fits-all synthetic hormone pill or cream isn’t the best answer.

The Two Types of Estrogen Replacement for Osteoporosis

There are two types of hormone replacement therapy: synthetic hormones created in a laboratory, and “bioidentical” replacement hormones that are derived from natural, plant-based sources.

Nothing that is created in a lab will ever be identical to what is found naturally in the body. But “bioidentical” hormones that are obtained from natural, living, plant-based sources are virtually identical in molecular structure to human hormones. So, the human body more readily “recognizes” bioidentical hormones, and they “fit” better with the body’s other cells. As a result bioidentical hormones – such as SottoPelle® Method estrogen replacement using subdermal pellets – are more effective than lab created hormones.

Bioidentical Estrogen Replacement is Safer for Osteoporosis

Because bioidentical hormone replacement therapy replicates the hormones that the body naturally produces, bioidentical estrogen replacement therapy is very safe for most perimenopausal, menopausal or post-menopausal women. The esteemed American Society for Reproductive Medicine, The North American Menopause Society, and The Endocrine Society have all unequivocally stated that most healthy, menopausal women can safely use estrogen replacement therapy for osteoporosis prevention.

(Note: A very small number of women with certain health issues – including women with breast or uterine cancer, liver disease, or a history of blood clots – may not be ideal candidates for estrogen therapy.  Estrogen replacement therapy Your doctor or a SottoPelle Method Certified Physician can help you decide if estrogen therapy is right for you.)

Ideally, the best time to begin estrogen replacement therapy for osteoporosis prevention is during early menopause. But, clinical studies have also demonstrated that estrogen replacement therapy can still preserve and protect bone mass, even when started more than a decade after the onset menopause!

Clinical Studies on Estrogen Replacement & Osteoporosis

A systematic clinical review entitled Bioidentical Hormone Replacement Therapy and Quality of Life in Postmenopausal Women was published this year (Maturitas; April 2023) found that bioidentical hormone replacement therapy significantly improved bone density in postmenopausal women. The study authors concluded that BHRT was an effective treatment for osteoporosis prevention.1

A study in the American Journal of Medicine also found that women receiving BHRT had a slower rate of bone loss compared to those not using hormone therapy – recognizing estrogen replacement therapy for its positive impact on bone mineral density and fracture prevention.

The esteemed American Society for Reproductive Medicine, The North American Menopause Society, and The Endocrine Society have also all unequivocally indicated that most menopausal women can safely use estrogen replacement therapy for osteoporosis prevention.

Pellets: The Best Estrogen Replacement Method

Estrogen replacement was originally delivered by a wide variety of methods: daily pills, messy gels and creams, unsightly patches, and painful shots. But SottoPelle® has “changed the game” of female hormone replacement with long-lasting, time-released sub-dermal estrogen pellets, that last from 3 to 5 months with a single insertion.

To begin with, estrogen pellets are much more convenient to use – with nothing to remember to take every day, no patches to replace, no sticky creams to apply, and no painful shots.

Even more importantly, hormone replacement pellets are by far more effective that other estrogen delivery methods. Clinical studies have shown that use of estrogen pellets resulted in four times the increase in bone density of oral estrogen pills, and 2.5 times more bone mass than hormone patches!

Additionally, unlike hormone pills, shots, or creams that put your body on a roller coaster of hormone dosage ups and downs, time-released estrogen pellets deliver hormones the same way the ovaries do – consistently and gradually over time, only as they are needed.

Estrogen Replacement Therapy

Bioidentical estrogen replacement therapy prevents osteoporosis by restoring the body’s natural hormone balance – rather than introducing lab-created chemicals that come with harsh and dangerous side effects.

It’s never too late to take steps to ensure that you are NOT in the 50% of women who will suffer a bone fracture due to osteoporosis. Ask your doctor if estrogen replacement therapy is the right treatment to help you maintain strong, healthy bones after menopause … and for the rest of your life!  Then insist on bioidentical estrogen replacement pellets for the safest, most consistent, 100% natural, and easiest-to-use form of hormone replacement.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


Why Hormone Replacement Therapy Should Be Part of Your Mommy Makeover

Women facing the physical changes of mid-life often find themselves searching for ways to look and feel younger. Pregnancy, childbearing, the stress of juggling work and family, and the toll of perimenopausal hormonal changes all take a toll on a woman’s face, skin, hair, and body.

While traditional mommy makeovers focus on cosmetic procedures, incorporating Hormone Replacement Therapy (HRT) into your makeover can offer a comprehensive transformation that goes beyond skin-deep improvements. In this article, the HRT experts at SottoPelle will explore how Hormone Replacement Therapy can enhance your mommy makeover journey by improving skin elasticity, revitalizing hair, and assisting with weight loss and muscle building.

Incorporating SottoPelle Method Hormone Replacement Therapy into your mommy makeover offers a holistic approach to rejuvenation that not only delivers superficial aesthetic results – but turns back the clock “from the inside out” for long lasting results that will help you look and feel younger for years to come.

Hormone Replacement Therapy Improves Skin Elasticity

As we age, declining hormone levels can lead to a loss of skin elasticity and the development of fine lines and wrinkles. HRT helps restore hormone levels, contributing to improved skin elasticity, reduced wrinkles, and a more youthful complexion. A mommy makeover with HRT ensures that your external transformation aligns with your internal revitalization.

Collagen is a protein that provides structural support to the skin, making it firm and resilient. With aging, collagen production naturally declines, leading to sagging and wrinkle formation. HRT, particularly with bioidentical hormones like estradiol and progesterone, can stimulate collagen synthesis. Estradiol, a form of estrogen, plays a crucial role in collagen production. By maintaining or restoring estrogen levels, HRT promotes collagen production, helping to maintain skin thickness and elasticity.

Elastin is another protein responsible for skin elasticity. It allows the skin to stretch and then return to its original state. HRT can help maintain elastin levels, preventing sagging and maintaining skin’s ability to “bounce back.” Healthy levels of estrogen contribute to elastin preservation.

Additionally, HRT can enhance the turnover of skin cells. Accelerated cell turnover ensures that new, healthier skin cells replace older ones more quickly. This can result in a smoother and more youthful complexion.

Hormone Replacement Therapy Improves Hair

Hair thinning and loss can be distressing for many women. HRT can help promote hair growth, thickness, and quality. Regaining luscious locks can be a significant confidence booster during your mommy makeover journey, giving you the hair you’ve always desired.

Estrogen plays a crucial role in hair follicle health. By maintaining or restoring estrogen levels, HRT can help counteract the effects of estrogen decline, which can lead to hair thinning. Hormones also play a role in regulating blood flow to the scalp and hair follicles. Estrogen, for instance, can improve blood circulation. By maintaining hormonal balance through HRT, blood flow to the scalp can be improved, enhancing the delivery of essential nutrients and oxygen to hair follicles.

Additionally, the hair growth cycle consists of several phases, with the anagen phase being the active growth phase. Hormonal imbalances can disrupt the hair growth cycle and shorten the anagen phase. By addressing hormonal imbalances, HRT can help prolong the anagen phase, allowing hair to grow longer and thicker. And, in some cases, hormonal imbalances can lead to the miniaturization of hair follicles, resulting in thinner, weaker hair. By correcting these imbalances, HRT may help prevent further follicle miniaturization and promote the growth of thicker, healthier hair.

Further, inflammation is a potential contributor to hair loss, particularly in conditions like alopecia areata. Hormones can influence the body’s inflammatory response. HRT can help regulate the inflammatory processes in the scalp, potentially reducing inflammation-related hair loss.

Hormone Replacement Therapy Assists with Weight Loss & Muscle Building

Perimenopause and menopause can be accompanied by weight gain and muscle loss. HRT supports the body in maintaining a healthy weight and building muscle. A mommy makeover that incorporates hormone replacement therapy will not only enhance your appearance but also empower you to feel strong and confident.

Estrogen, a key female hormone, plays a vital role in regulating body composition. It helps maintain lean body mass and supports the balance between muscle and fat. When estrogen levels decline during menopause or due to hormonal imbalances, women often experience an increase in body fat and a reduction in muscle mass. HRT with estrogen can help restore this balance, preventing fat accumulation and promoting muscle preservation and growth.

Estrogen also influences metabolism. It aids in maintaining a healthy metabolic rate, which determines how efficiently the body burns calories and uses energy. HRT can enhance metabolic rate by maintaining or restoring estrogen levels, resulting in increased calorie expenditure, and facilitating weight loss.

Hormone replacement therapy, particularly to balance testosterone, can stimulate muscle protein synthesis. This process involves the creation of new proteins within muscle cells, leading to muscle growth and repair. HRT increases the availability of these anabolic hormones, promoting muscle development.

HRT contributes to a shift in body composition, favoring the increase in lean muscle mass and the reduction of body fat. This change is essential for improving metabolic rate, as muscle tissue burns more calories at rest than fat.

Hormone Replacement Therapy “Mommy Makeover”

The SottoPelle Method offers a unique and personalized approach to hormone replacement therapy. With a focus on bio-identical hormones, this method ensures that HRT aligns perfectly with your body’s needs. Whether you’re looking to improve skin elasticity, revitalize your hair, shed unwanted pounds, or build muscle, adding SottoPelle Method hormone replacement therapy to your mommy makeover journey can help you look and feel years younger.

For moms and middle-aged women seeking a comprehensive transformation, HRT can be the missing piece of the puzzle. SottoPelle Method bioidentical hormone replacement therapy offers a safe, natural, personalized approach to HRT, ensuring that your mommy makeover aligns with your body’s unique needs and your aesthetic desires, both inside and out.

If you are a “mommy” or middle-aged women who is ready to combat the physical, emotional, and aesthetic changes of mid-life, talk to your doctor about SottoPelle Method hormone replacement therapy today.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


Natural Medicine & Hormone Replacement: Integrative, Functional, Naturopathic & Holistic Approaches

The traditional approach to medicine, while effective in treating specific diseases, has sometimes overlooked the uniqueness of each patient. As a result, a growing number of individuals are now seeking alternative approaches that focus on holistic and natural remedies, aiming to prevent disease by promoting balance within the body.

However, the term “natural medicine” can be interpreted differently and mean different things to different people. In this article, we explore the distinctions between Integrative Functional Medicine, Naturopathic Medicine, and Holistic Medicine, shedding light on their definitions and guiding philosophies.

Integrative Medicine

Integrative Medicine is an approach that combines conventional medical treatments with evidence-based complementary therapies. This discipline acknowledges that healing extends beyond treating symptoms and focuses on the whole person: body, mind, and spirit. Integrative medicine doctors work in partnership with patients to create individualized treatment plans that address the root causes of health issues while considering lifestyle, diet, emotional well-being, and environmental factors.

Integrative Medicine believes in treating the whole person and emphasizes the importance of the patient-physician relationship. It integrates the best of both conventional and complementary approaches to optimize health and healing outcomes.

Functional Medicine

Functional Medicine is a patient-centered approach that aims to identify and address the underlying root causes of disease. It utilizes a systems-oriented perspective, considering the intricate connections within the body and how various factors influence health.

Rather than merely treating symptoms, functional medicine seeks to restore balance and proper functioning to support the body’s inherent healing mechanisms.

Functional medicine also emphasizes personalized care, focusing on individualized treatment plans tailored to each patient’s unique needs. By identifying and addressing the underlying factors driving disease, functional medicine doctors seek to prevent chronic illnesses and promote long-term health and well-being.

Naturopathic Medicine

Naturopathic Medicine, also known as Natural Medicine, is a holistic approach that emphasizes the body’s innate ability to heal itself. Naturopathic doctors use natural therapies and non-invasive techniques to support the body’s healing processes. These may include botanical medicine, nutrition, lifestyle counseling, homeopathy, supplements and sometimes physical manipulation.

Naturopathic Medicine is guided by six fundamental principles: First, do no harm; the healing power of nature; treat the cause, not just the symptoms; treat the whole person; prevention is the best cure; and the physician as teacher. Naturopathic doctors also strive to uncover the root cause of illness and prioritize patient education and self-care to empower individuals to take charge of their health.

Holistic Medicine

Holistic Medicine refers to an approach that considers the whole person – body, mind, emotions, and spirit – in the context of their environment. This approach acknowledges that imbalances in one aspect of life can impact overall health and well-being. Holistic doctors seek to restore balance and harmony in all areas of life to promote optimal health.

Holistic Medicine doctors believe that the mind and body are interconnected, and that each person is unique. The focus is on prevention, self-healing, and maintaining wellness by addressing the root causes of imbalances and empowering patients to make positive lifestyle choices.

Conclusion: As more individuals seek alternatives to conventional medicine, the terms “integrative medicine,” “functional medicine,” “naturopathic medicine,” and “holistic medicine” have become increasingly prevalent. Each of these approaches carries unique definitions and philosophies but shares the common goal of promoting holistic health and well-being. By recognizing and understanding the distinctions between these disciplines, patients can make informed decisions about their healthcare, working towards a healthier, balanced life.

Overlap of Natural Medicine Practices

As you can see, it is easy to recognize that there is significant overlap among Integrative Functional Medicine, Naturopathic Medicine, and Holistic Medicine. Doctors and other healthcare professionals are increasingly integrating elements from all these disciplines into their practice – in addition to also offering traditional and conventional medicine modalities.

This allows doctors to provide comprehensive and personalized care, tailoring treatments to suit the individual needs of each patient. By drawing from a diverse range of therapeutic options, doctors can address a wide spectrum of health concerns, promoting healing and well-being from multiple angles. This approach also more fully empowers patients to manage their own health – and encourages a collaborative and patient-centered relationship between doctor and patient.

Why Bioidentical Hormone Replacement Therapy is a Natural Treatment

Bioidentical Hormone Replacement Therapy (BHRT) is a treatment that has gained significant acceptance and adoption among practitioners of Integrative, Functional, Naturopathic, and Holistic Medicine – as a natural treatment for many conditions – as well as an effective disease preventive.

There are several compelling reasons why natural medicine doctors embrace Bioidentical Hormone Replacement Therapy as a valuable tool in their practice. To begin with, one of the primary reasons BHRT is favored is that it uses hormones that are identical in structure to the hormones naturally produced by the human body.

Unlike synthetic hormones, which have a slightly different molecular structure, bioidentical hormones are derived from plant sources and precisely match the hormones present in the body. This molecular similarity allows BHRT to be better recognized and utilized by the body’s hormone receptors, leading to more efficient and targeted therapeutic effects.

Additionally, BHRT simply replaces what is missing or out of balance. Bioidentical Hormone Replacement Therapy operates on the principle of restoring hormonal balance in the body. Rather than introducing new medications or chemicals to treat symptoms, BHRT simply replenishes the body’s hormones that may be deficient or imbalanced due to factors such as aging, menopause, or other medical conditions.

BHRT is also safer and has fewer side effects than synthetic hormones. Compared to synthetic hormones, bioidentical hormones are believed to have a lower risk of adverse effects and complications. Since bioidentical hormones mimic the body’s natural hormones, they are generally better tolerated and have a reduced likelihood of causing unwanted side effects.

In many cases, Bioidentical Hormone Replacement Therapy can help patients avoid the need for harsh medications and surgery. For certain hormone-related conditions and imbalances, BHRT can provide an effective and non-invasive solution, potentially reducing the need for more aggressive medical interventions like surgery or the use of strong pharmaceuticals. By restoring hormonal equilibrium through BHRT, doctors can help patients avoid the potential risks and complications associated with harsh treatments, while still achieving positive health outcomes.

Natural Hormone Replacement Therapy

Bioidentical Hormone Replacement Therapy is embraced by most doctors practicing Integrative Functional Medicine, Naturopathic Medicine, and Holistic Medicine due to its use of hormones identical to the body, its ability to restore hormonal balance naturally, its favorable safety profile compared to synthetic hormones, and its potential to offer a gentler, less invasive alternative to harsh medications and surgeries.

If you are suffering from symptoms of aging, menopause, sexual dysfunction, osteoporosis, cardiac disease, or other diseases and imbalances of the body, incorporating BHRT into your treatment plan may be the natural alternative that is right for you.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


Relieving Symptoms of Hypothyroidism & Hashimoto’s Thyroiditis

Are you suffering from fatigue, weight gain, cold intolerance, constipation, brain fog, and other unexplained symptoms? You may be suffering from hypothyroidism and/or Hashimoto’s thyroiditis – conditions in which the thyroid gland stops producing sufficient levels of essential thyroid hormones.

These conditions often go undiagnosed for a significant period, leaving many patients unaware of their underlying thyroid disorders. In many cases women and men just write-off these symptoms as “part of getting older” or “side effects of menopause” and don’t seek treatment at all. In other cases, patients may wait until they see their primary care doctor (rather than a specialist) who just prescribes a one-size-fits all thyroid medication – that really doesn’t make much of a dent in the patient’s symptom or their underlying condition (which typically gets worse without appropriate intervention.)

The good news is that with specialized diagnosis, treatment, and monitoring, patients who are suffering from hypothyroidism and/or Hashimoto’s Disease CAN regain their quality of life and live life with comfort, health and vitality.

Understanding “Hypo” Thyroid Diseases

Hypothyroidism is characterized by an underactive thyroid gland, leading to symptoms such as fatigue, weight gain, cold intolerance, constipation, and brain fog. Hashimoto’s thyroiditis is a specific autoimmune disorder, where the body’s immune system mistakenly attacks and damages the thyroid gland – causing chronic inflammation and progressive damage to the thyroid gland, ultimately resulting in hypothyroidism.

Unfortunately, the subtlety and gradual onset of hypothyroid symptoms often lead individuals and their primary care doctors to dismiss them – or to attribute them to other causes – causing delayed recognition and diagnosis. Consequently, many patients remain unaware that their frustrating, ongoing symptoms may be attributed to thyroid dysfunction.

Treating Hypothyroidism with BHRT

Conventional treatment options for hyperthyroidism and Hashimoto’s disease include the prescription of thyroid hormone replacement medications. However, as with any medical treatment, a “flat rate” or “one-size-fits-all” approach is never as effective as a customized, individual treatment plan with ongoing monitoring.

Bioidentical hormone replacement therapy involves the use of hormones that are structurally and functionally identical to those naturally produced by the body. In the context of thyroid disorders, BHRT aims to restore thyroid hormone balance and alleviate the associated symptoms experienced by individuals with hypothyroidism or Hashimoto’s thyroiditis.

BHRT provides a personalized approach to hormone replacement therapy, tailored to the unique needs of each individual. Through comprehensive evaluation and hormone testing, healthcare providers can determine the specific imbalances and deficiencies in thyroid hormones. Based on these assessments, BHRT can be customized to supplement deficient thyroid hormones in a form that mimics the body’s natural hormones.

One of the primary advantages of BHRT is the potential for individualized dosing and optimization of thyroid hormone levels. This customization allows for a fine-tuning of therapy, aiming to achieve optimal hormone balance for each patient. By restoring thyroid hormone levels to the appropriate range, BHRT may help alleviate symptoms commonly associated with hypothyroidism and Hashimoto’s thyroiditis, such as fatigue, weight gain, brain fog, and other related concerns.

BHRT as an Adjunct Therapy for Hypothyroid Disease

Bioidentical hormone replacement therapy (BHRT) is also being explored for its potential as an adjunct therapy for certain thyroid conditions.

Medical doctors who take an integrative approach may incorporate a combination of modalities to restore health and vitality in patients with hormone disorders such as hypothyroidism. This may include medications, lifestyle modifications, dietary changes, stress management techniques, targeted supplementation, and, in some cases, bioidentical hormone replacement therapy (BHRT).

The goal is to address the underlying causes of hormone imbalances and support the body’s natural healing processes. By leveraging blood tests and ongoing monitoring, integrative medicine doctors can track progress, fine-tune treatment plans, and achieve optimal hormone balance for their patients.

BHRT for Treating Hypothyroid Disease

While BHRT is not a replacement for conventional treatment for individuals with hypothyroidism and Hashimoto’s thyroiditis, BHRT offers a potential as an adjunct therapy, helping to restore thyroid hormone balance and alleviate associated symptoms. By tailoring hormone replacement to each individual’s specific needs, SottoPelle® Method certified doctors provide a personalized approach to address hormonal imbalances.

Comprehensive blood tests play a crucial role in evaluating hormone levels and identifying imbalances, serving as a valuable tool in the hands of SottoPelle® Method certified doctors. By utilizing ongoing monitoring and close observation, integrative medicine doctors strive to restore optimal health and vitality for their patients.

If you have been suffering from fatigue, anxiety, weight gain, brain fog, sadness, low libido, unexplained pain, or other frustrating symptoms that your current doctors aren’t explaining, a SottoPelle® Method certified doctor can help! Physicians who have undergone SottoPelle® Method training and certification are trained in recognizing, diagnosing, and treating hormonal imbalances that are impacting your health and quality of life. Once a diagnosis has been made, your SottoPelle® Method certified doctor can determine if bioidentical hormone therapy is right for you.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


Why Doctors Miss & Misdiagnose Many Diseases in Older Women

Women’s healthcare has indeed made significant strides since the 1800s when female patients were often subjected to dismissive attitudes and inaccurate diagnoses like “hysteria” or “the vapors.” Sadly, during that time, women’s symptoms – particularly those related to mental health or reproductive issues – were frequently disregarded or attributed to imagined ailments.

Thankfully, recent advancements in medical understanding and societal progress have brought about substantial improvements in women’s healthcare. Recognition and acknowledgement of women’s unique healthcare needs have played a vital role in this transformative journey. And over the years, medical professionals and researchers have worked diligently to dismantle the prevailing biases and misconceptions that hindered comprehensive women’s healthcare.

Unfortunately, in spite of significant advancements in women’s healthcare, many traditional doctors still continue to dismiss, misdiagnose, and mistreat various diseases in female patients – particularly in older women. In this article the hormone replacement experts at SottoPelle® Method address the underlying reason for this bias in healthcare – and offer solutions for accurate and effective treatment of women’s medical conditions.

Bias in Diagnosing & Treating Diseases in Older Women

One contributing factor to the misdiagnosis and mistreatment of diseases in older women is the age and gender biases that still prevail within the medical community. Symptoms and presentations of diseases in older women often differ substantially from those typically seen in younger patients or male counterparts, making diagnosis more complex. However, some doctors may dismiss or trivialize these symptoms, attributing virtually everything to age or menopause without conducting thorough evaluations.

This leads to missed or delayed diagnoses, depriving women of the timely intervention, and new advancements in female medical care that they truly need.

Furthermore, societal stereotypes and ingrained biases can also influence healthcare providers’ perceptions of older women. Ageism and sexism can contribute to a lack of attentiveness and empathy, resulting in inadequate medical assessments and treatment plans. Stereotypes of women being “hormonal” or “overly emotional” can lead unenlightened doctors to dismiss their patients’ concerns as “overreacting” – or to consider their symptoms “psychosomatic”, e.g. “all in their head.”

As a result, women may face prolonged suffering, worsening health conditions, and decreased quality of life due to the failure to recognize and address their specific healthcare needs.

While “getting older” can be a contributing factor to many women’s health issues – from sex drive, to incontinence, weight gain, memory loss, and more – that does not mean these conditions are just something women must “learn to live with”.

This is because it is not “age” itself that causes these issues – but it is the hormonal decline that comes with getting older that can be at the root of these and many other female health problems. And when doctors take the time to investigate, diagnose, and treat a woman’s underlying health conditions – rather than dismissing symptoms as “natural aging” – women can experience health and vitality at any age.

Conditions Commonly Missed or Misdiagnosed in Women

Several diseases and conditions in older women are commonly ignored, misdiagnosed, or mistreated, leading to significant health consequences.

Hormone imbalances, such as menopause-related changes, disorders like polycystic ovary syndrome (PCOS), and thyroid dysfunction, are frequently disregarded or misunderstood. The symptoms associated with these conditions, such as hot flashes, mood swings, fatigue, weight gain, and irregular menstrual cycles, are sometimes attributed to “normal aging” and considered “minor inconveniences” by some traditional doctors. As a result, women may not receive the appropriate hormone therapy or interventions to alleviate their symptoms, affecting their quality of life and potentially exacerbating other health issues.

Another commonly ignored and misdiagnosed condition in older women is osteoporosis. As women age, their bone density naturally decreases, making them more susceptible to fractures. However, osteoporosis is often undetected until a fracture occurs, as routine screenings for bone health are not always emphasized. This delay in diagnosis and treatment puts older women at an increased risk of suffering from debilitating fractures and related complications.

Additionally, cardiovascular diseases, including heart disease and heart attacks, can be underdiagnosed, and undertreated in older women. The presentation of symptoms in women may differ from the classic symptoms seen in men, leading to misinterpretation or dismissal. Women may experience atypical signs such as fatigue, shortness of breath, nausea, or abdominal discomfort, which are often attributed to other conditions, resulting in delayed diagnosis and treatment.

Further, mental health conditions, particularly depression and anxiety, are frequently overlooked in older women. Symptoms of depression may also be mistaken as a normal part of aging or attributed to other medical conditions. The complex interplay between hormonal changes, life transitions, and social factors can contribute to the development or exacerbation of mental health issues, making it crucial to identify and address these conditions to ensure proper support and treatment.

Diagnosing Women’s Health Issues

Addressing women’s health concerns requires an integrative and multi-faceted approach. First and foremost, medical education and training programs must emphasize the importance of gender-specific healthcare and the unique health challenges faced by older women. Healthcare providers need to be equipped with the knowledge and skills to recognize and address the complexities of women’s health, including the impact of age-related hormonal shifts, and other coexisting medical conditions.

Empowering women to advocate for themselves, seek second opinions, and actively participate in their medical decision-making process can help combat misdiagnoses and mistreatment. Women should feel emboldened to voice their concerns, share their experiences, and insist on thorough evaluations and appropriate interventions.

Hormone Therapy for Women’s Health

Hormones affect every aspect of a woman’s body, including physical, mental, emotional, and sexual functioning. So, understanding and addressing hormone decline in older women can be an excellent first step in diagnosing and treating women’s health issue and their associated symptoms.

SottoPelle® Method 100% natural bioidentical hormone therapy can help restore a woman’s body and mind to optimal balance as she ages – in addition to protecting a woman’s body from a wide variety of diseases including type 2 diabetes, heart disease and osteoporosis. In fact, recent research has clearly shown that combined HRT use is linked to an overall lower risk of death in women from all causes after menopause!

And SottoPelle® Method hormone replacement therapy pellets offer several advantages, including NO daily pills, NO painful weekly shots, and NO messy creams. Additionally, SottoPelle® Method pellet therapy utilizes bioidentical hormones that are safer, more effective, and more natural than lab-created synthetics. Because bioidentical hormones are identical to the body’s own hormones, they offer more effective results, with fewer side-effects and risks.

Diagnosing & Treating Women’s Health Issues

While challenges and disparities still exist in women’s health care, the advancements made over the past century are undeniable. The transition from dismissive attitudes and outdated beliefs to a more inclusive, patient-centered, and evidence-based approach is evolving thanks to dedicated healthcare professionals, researchers, and advocates – like the hundreds of SottoPelle® Method certified doctors across the US.

As we move forward, it is crucial to continue building on this progress, striving for gender equity, and ensuring that women receive the high-quality healthcare they deserve at every stage of their lives.

If you have been suffering from fatigue, anxiety, weight gain, brain fog, sadness, low libido, unexplained pain, or other frustrating symptoms that your current doctors aren’t explaining, a SottoPelle® Method certified doctor can help! Physicians who have undergone SottoPelle® Method training and certification are trained in recognizing, diagnosing, and treating hormonal imbalances that are impacting your health and quality of life. Once a diagnosis has been made, your SottoPelle® Method certified doctor can determine if bioidentical hormone therapy is right for you.

And because the symptoms associated with hormone decline can also be caused by other medical conditions, a SottoPelle® Method certified doctor can also help to rule out other potential causes of your symptoms and develop a comprehensive treatment plan that addresses your individual needs.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


Three Ways BHRT Can Promote Brain Health

Most people know that maintaining heart and artery health, staying in physical shape, and taking care of your body is the key to a long and active life. But many men and women don’t give much thought to taking care of their brain.

In this article, the hormone therapy experts at SottoPelle® explore the importance of brain health, and discuss how maintaining optimal hormone balance in your body can protect the brain from decline and reduce the risk of debilitating cognitive disease.

Why Brain Health is Important

Brain health is a fundamental aspect of overall well-being, encompassing not only our cognitive abilities and day-to-day functioning but also our happiness and overall quality of life. The brain serves as the control center for our thoughts, emotions, memories, and behaviors, intricately influencing every aspect of our existence.

When the brain is in optimal condition, it allows us to process information efficiently, make sound decisions, maintain emotional stability, and foster meaningful relationships. A healthy brain empowers us to engage with the world, pursue our passions, and experience a sense of fulfillment.

Conversely, impaired brain function can lead to cognitive decline, mood disorders, and a diminished ability to navigate life’s challenges. Therefore, safeguarding and enhancing brain health is vital not only for the sake of functioning but also for fostering happiness, well-being, and an enriched quality of life.

BHRT and Brain Health

The hormones present in the human body regulate or influence almost every aspect of mental and physical functioning. Most people have already experienced the effects of hormones on the brain to some degree. For example, the mood swings associated with puberty, pregnancy, and menopause are all driven by spikes or declines in hormone levels.

But, as we age, our hormone levels naturally decline – and so does our “cognition,” including memory and mental sharpness.

In men, the most well-known hormonal change associated with aging is a gradual decline in testosterone levels. Research suggests that testosterone levels decrease by approximately 1% per year after the age of 30. By the time men reach their 70s or 80s, testosterone levels can be significantly lower compared to their younger years.

In women, hormonal changes are more complex due to the menopausal transition. During perimenopause, which typically begins in the late 30s to early 40s, hormone levels, particularly estrogen and progesterone, may fluctuate irregularly. As women progress through menopause, usually occurring around the age of 50, estrogen and progesterone levels decline more significantly. On average, women experience a decrease in estrogen levels of approximately 35% to 75% during menopause.

The good news is that bioidentical hormone replacement therapy (BHRT) can restore hormone balance – which can slow or reverse many of the signs of aging, including cognitive decline.

Improving Brain Health with BHRT

There are a number of things that individuals can do to preserve their cognition and memory, including a brain-healthy diet, supplements, staying mentally active, doing puzzles and other ‘brain teasing’ activities, and of course quitting smoking. But if the brain does not have the hormones it needs to function properly, these activities alone will not be successful.

BHRT (bioidentical hormone replacement therapy) is a 100% natural treatment that uses hormones that are chemically identical to those produced by the human body to restore optimal hormonal balance. BHRT is well known as an effective protocol to treat a wide variety of conditions, including menopause, andropause, “Low T,” sexual dysfunctions and more.

But a growing body of clinical research evidences the fact that BHRT may also has significant cognitive benefits. The potential cognitive benefits of BHRT, include:

  • Improved mental health conditions related to dopamine and serotonin
  • Preserved cognition and memory as men and women age
  • Preventing Alzheimer’s disease
  • Improving cognitive function in people with Alzheimer’s disease

(1.) BHRT for Preserving Cognition and Memory

A number of studies have shown that BHRT can preserve cognition and memory in older adults. For example, a study published in the journal “Menopause” found that BHRT was able to improve verbal memory and executive function in women with menopause.

Another study, published in the journal “Neurology”, found that BHRT was able to slow the decline of cognitive function in older adults. The study found that people who received BHRT had a slower decline in cognitive function than those who did not receive BHRT.

These studies indicate that BHRT can be an effective treatment for preserving cognition and memory in older adults. And, in fact, our SottoPelle® Method providers have seen and treated thousands of women whose menopausal “brain fog” cleared up completely after restoring their hormone balance with HRT.

(2.) BHRT for Improving Mental Health Conditions

Dopamine and serotonin are neurotransmitters that play a role in mood, behavior, and cognition. Low levels of dopamine and serotonin have been linked to a number of mental health conditions, including depression, anxiety, and ADHD.

However, recent clinical studies have shown that BHRT may be able to improve mental health conditions related to dopamine and serotonin. For example, a study published in the journal “Depression and Anxiety” found that BHRT was able to improve symptoms of depression in women with low levels of estrogen.

Another study, published in the journal “Biological Psychiatry”, found that BHRT was able to improve symptoms of ADHD in men with low levels of testosterone.

These recent studies provide evidence that restoring hormone balance with BHRT may be a promising treatment for mental health conditions related to dopamine and serotonin.

(3.) BHRT for Preventing Alzheimer’s Disease

Alzheimer’s disease is a neurodegenerative disorder that is characterized by the progressive decline of cognitive function. The most common symptoms of Alzheimer’s disease are memory loss, difficulty with language, and problems with thinking and judgment.

There is no cure for Alzheimer’s disease, but there are treatments that can help to slow the progression of the disease and improve cognitive function. One of these treatments is BHRT.

A number of studies have shown that BHRT can improve cognitive function in people with Alzheimer’s disease. For example, a study published in the journal “Nature Medicine” found that BHRT was able to improve verbal memory, executive function, and overall cognitive function in people with Alzheimer’s disease.

Another study, published in the journal “Neurology”, found that BHRT was able to slow the progression of Alzheimer’s disease. The study found that people who received BHRT had a slower decline in cognitive function than those who did not receive BHRT.

These studies suggest that BHRT may be a promising treatment for Alzheimer’s disease.

How BHRT Improves Brain Health

The specific metabolic mechanisms by which BHRT produces cognitive benefits are still being studied. However, scientists do know that there are a number of processes working in a healthy brain that BHRT can support.

To begin with, it is believed that BHRT helps to protect the brain from damage. BHRT has been shown to increase levels of antioxidants in the brain, which can help to protect against damage caused by free radicals.

BHRT also helps to improve blood flow in the body – including to the brain. This is important because blood flow is essential for delivering oxygen and nutrients to the brain. BHRT is also understood to improve the function of neurotransmitters – the chemicals that allow nerve cells to communicate with each other.

SottoPelle® Method BHRT for Brain Health

There is a continually growing body of clinical research that demonstrates the brain health benefits of maintaining hormone balance with BHRT.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


Natural Male Infertility Treatment with Bioidentical Hormone Therapy

If you are trying to become pregnant without success, you are not alone. According to the World Health Organization (WHO), infertility affects approximately 15% of couples – meaning that one in every six couples experiences difficulty in achieving pregnancy or carrying a pregnancy to term.

While infertility was traditionally thought to be primarily a female issue, more recent studies have shown that male infertility is a significant contributor to the problem. According to the American Society for Reproductive Medicine, male infertility is a factor in approximately 30% to 40% of infertility cases.

Unfortunately, rather than addressing the underlying cause of male infertility, many couples immediately jump to extremely expensive artificial or assisted methods of conception, such as IVF. However, many of the medical conditions affecting male fertility can actually be treated naturally.

Bioidentical hormone therapy is one natural method of treatment that has shown exceptional promise for treating many of the underlying imbalances causing male infertility. In this article, the bioidentical hormone therapy experts at SottoPelle® Method discuss the male hormones involved in fertility – and how imbalances in these hormones can impact numerous glands in the body, including the hypothalamus, thyroid gland, pituitary gland, prostate, and testicles.

The High Cost of Artificial Fertility Treatments

IVF and other artificial fertility treatments can be prohibitively expensive. The average cost of an IVF cycle in the United States can range from $12,000 to $15,000, which does not include the cost of medication or additional diagnostic tests.

Other artificial fertility treatments, such as intracytoplasmic sperm injection (ICSI) or assisted hatching, can also add to the exorbitant overall cost. Additionally, insurance coverage for fertility treatments varies significantly, and many insurance policies do not cover artificial and assisted fertility procedures at all. This leaves couples to pay tens of thousands of dollars out of pocket.

The high cost of artificial fertility treatments can make them out of reach for many couples, leading to financial strain and potentially causing them to forgo treatment altogether. Other couples may seek alternative options, such as adoption or using a donor egg or sperm, which may still involve significant financial and emotional investments.

Hormonal Imbalances That Can Affect Male Fertility

Male infertility affects millions of men worldwide and can be caused by a variety of factors. But one of the most common underlying causes of male infertility is hormonal imbalance.

Testosterone is the primary male sex hormone, and it plays a crucial role in the development of male reproductive organs, sperm production, and sex drive. Other hormones involved in male fertility include follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin. FSH and LH are produced by the pituitary gland and are responsible for regulating testosterone production and sperm production in the testicles. Prolactin is produced by the pituitary gland and plays a role in sexual function and fertility.

Hormonal imbalances can occur when there is an excess or deficiency of one or more hormones in the body. Imbalances in male hormones can impact numerous glands in the body, including the hypothalamus, thyroid gland, pituitary gland, prostate, and testicles.

Low testosterone levels can lead to reduced sperm production and decreased sex drive. High levels of the hormones estrogen and/or prolactin can interfere with the production of testosterone and sperm. Low levels of LH or FSH can also lead to decreased testosterone and sperm production. Thyroid disorders can also lead to imbalances in the male hormones that regulate fertility.

Treating Male Infertility with Bioidentical Hormone Therapy

Bioidentical hormone therapy (BHT) has been shown to be a promising treatment option for certain men who are experiencing infertility due to hormonal imbalances. Bioidentical hormone therapy involves using hormones that are identical in chemical structure to those produced naturally by the body. BHRT can help to restore hormonal balance, which in turn can help a man’s body improve sperm production and quality.

Testosterone replacement therapy (TRT) is a common form of bioidentical hormone therapy for men with low testosterone levels. Administering testosterone using bioidentical hormone therapy can help to improve sperm production and increase sex drive in many men.

Other forms of bioidentical hormone therapy, including human chorionic gonadotropin (hCG) and clomiphene citrate, can help to increase LH and FSH levels, which can also improve testosterone and sperm production in some male patients.

Male Sperm Problems that Bioidentical Hormone Therapy May Help

Azoospermia is a condition in which there is a complete absence of sperm in a man’s ejaculations. Bioidentical hormone replacement therapy can be used to treat azoospermia by addressing hormonal imbalances that may be contributing to the condition. For example, low levels of testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) can all contribute to azoospermia, and bioidentical hormone replacement therapy can be used to increase levels of these hormones to help restore fertility.

Oligospermia is a condition in which there is a low sperm count in a man’s ejaculations. Asthenospermia is a condition in which there is poor sperm motility or movement. Bioidentical hormone replacement therapy can be used to treat both of these conditions by addressing low levels of testosterone, LH, and FSH which can all be contributing factors to these conditions.

Teratozoospermia is a condition in which a man has a high percentage of abnormally shaped sperm – which interferes with their ability to successfully fertilize an egg. Low levels of testosterone, LH, and FSH can all contribute to teratozoospermia, and bioidentical hormone replacement therapy can be used to increase levels of these hormones to help improve sperm shape. Additionally, bioidentical hormone replacement therapy can be used to address imbalances in thyroid hormone and cortisol, which can also impact sperm health.

SottoPelle® Method Bioidentical Hormone Therapy for Male Infertility

If you have been suffering from the heartache of infertility, a SottoPelle® Method certified doctor may be able to help restore your body to balance – so you can conceive naturally without expensive and exhausting artificial fertility methods.

Physicians who have undergone SottoPelle® Method training and certification are trained in recognizing, diagnosing, and treating hormonal imbalances that are impacting all aspects of a patient’s health and quality of life. Through thorough blood testing, your SottoPelle® Method certified doctor can determine if you have hormone imbalances or deficiencies that may be affecting your sperm quality and your ability to conceive.

If you’re experiencing symptoms of hormonal imbalances or infertility, it’s important to discuss your concerns with a SottoPelle® Method Certified Doctor who can help you determine if bioidentical hormone therapy is right for you – and develop a comprehensive treatment plan that addresses your individual needs to improve your chances of naturally growing your family.

Call 201-225-2525 or schedule a consultation at:

Article created by SottoPelle and used by permission of SottoPelle. Advanced Hormone Solutions is a “Certified” SottoPelle provider


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