Are You Risking Your Health with SYNTHETIC Hormone Replacement Therapy (HRT)?

Heed the Label Warnings!

If you are taking pharmaceutical HRT, you already know that it comes with a list of serious risks and warnings from the FDA1. Decades of research dating as far back as the early days of Premarin link conjugated and synthetic hormones with uterine cancer and other life-threatening diseases. One of the most notorious studies was the Women’s Health Initiative sponsored by the National Institutes of Health (NIH) and the National Heart, Lung, and Blood Institute (NHLBI). The estrogen plus progestin vs placebo trial was abruptly halted in 2002 due to health safety issues. It was determined that women taking conjugated estrogen with a synthetic progesterone (progestin) were at greater risk of blood clots, strokes, heart attacks and breast cancer than those taking the placebo. The estrogen-only study was likewise terminated in 2004. As a result of these alarming events, millions of women stopped taking their pharmaceutical HRT.

A follow-up study, reported in the American Journal of Public Health in 2013, assessed the effects of that massive exodus. It was estimated that “over a 10-year span, starting in 2002, a minimum of 18, 601 and as many as 91, 610 postmenopausal women died prematurely because of the avoidance of estrogen therapy (ET).”2

The fact is your body needs its sex hormones to function properly no matter what age you are. Receptors for estradiol (a woman’s most important estrogen), testosterone and progesterone exist throughout your body performing many beneficial roles beyond sexual function, including protecting your bone, cardiovascular, breast and brain health.

But, if synthetic HRT is dangerous and your body still needs hormones, what’s the answer?

Bioidentical Hormones Are Healthier and Safer Alternatives

The grip that pharmaceutical companies have on the HRT industry remains formidable. Despite positive evidence of the benefits of using bioidenticals, many mainstream doctors still prescribe standard-dose synthetics.

Even so, did you realize that bioidentical hormones have been widely used around the world since the 1930s? In addition, a great deal of medical literature attests to the fact that they are safer and more effective than their synthetic counterparts.3,4 This is because bioidentical hormones are exact molecular matches for those your body makes. And it takes an exact hormone match (whether estrogen—specifically estradiol–progesterone or testosterone) in a precise amount to fully communicate with and command receptor cells. The body recognizes bioidentical hormones in totality and works with them to perform many body functions beyond symptom relief. Synthetics, on the other hand, do not match human hormones and that’s where the trouble begins.

Do Your Homework

Replacing only your estrogen will not result in hormonal balance. You need to find an expert who understands what it takes to achieve that internal balance. One who provides a safe and effective treatment that can restore your hormones to beneficial levels without the health risks, guesswork or trial and error. (Too much of a good thing is still too much, and too little will do little.)

We are all of the above. SottoPelle® is recognized around the world as a leader and expert in science-based, cutting-edge BHRT. Join thousands of other men and women who are enjoying life again. Experience for yourself the SottoPelle® difference!


3 Reasons You Aren’t Sleeping Well

On average, you need at least 6 hours of sleep to waken feeling fully rested. It’s been shown to encourage sleep if you go to bed at the same time each night, which should be around 10:30 to 11 p.m. It’s also a good idea to rise around the same time each morning. Earlier is better than later.

Most of us experience sleep issues at one time or another during our lives. But as you get older you may find that happening on a regular basis. Your insomnia may even become chronic and take its toll on your health. Let’s take a look at what could be causing you to toss and turn, and some things you can do that will help.

Why You Aren’t Sleeping Well

1) PROBLEM: Too much TV!
Insomnia has been linked to excessive TV watching. It seems that overexposure to the bright light emitted from your TV screen (or your iPad or smartphone for that matter) can negatively affect your melatonin production. It’s thought that using these devices at night tricks the brain into thinking it isn’t time for sleep.

SOLUTION: Cut off the TV or other devices at least an hour before bedtime, preferably two. You might also want to remove all of your electronics from your bedroom and use this room just for sleeping. Instead of watching TV, read an inspirational book, listen to relaxing music, or use this quiet time for meditation or prayer before retiring to the bedroom.

2) PROBLEM: Too much to drink!
Alcohol can make you drowsy and help you fall asleep, but it deprives you of the deep sleep you really need. A glass of wine with dinner won’t put a dent in your slumber. However, consuming several drinks before bedtime can have you waking in the middle of the night, unable to get back to sleep. If you frequently drink before bed, you will find yourself chronically drained and exhausted from lack of deep sleep.

SOLUTION: Alcohol should not be used as a sleep aid. Nor should you depend on medications, which also rob you of REM sleep. Instead, create a new relaxation routine that will encourage sleep. You might want to begin an exercise regime that gets you outside during the day. Merely walking at a moderate pace for a half hour daily can reduce the time it takes to fall asleep, help you sleep longer and get better quality sleep.

3) PROBLEM: Not enough hormones!
Problems with endocrine hormones affect both men and women who are experiencing perimenopause, menopause or andropause. At this stage of life, hormonal imbalance prevails. Insomnia is a typical side effect of fluctuating or depleted hormones.

SOLUTION: Get your hormones checked! If you are deficient in testosterone, estradiol or thyroid, you can likely benefit from a safe and effective bioidentical hormone replacement therapy such as SottoPelle®. Not only will it alleviate symptoms of hormone deficiency and help you get better rest, our BHRT is the perfect foundation for a healthier, happier life as you age.

Parkinson’s Awareness Month

April is Parkinson’s Awareness Month. Parkinson’s Disease (PD) is estimated to afflict seven to ten million people worldwide and approximately one million in the U.S. This chronic and progressive movement disorder occurs when part of the brain deteriorates due to dopamine deficiency. Dopamine impacts movement, emotional response and the ability to feel pleasure. The severity of the disease differs from person to person. So far, there is no cure, but researchers are hopeful.

Research evidence is showing that exercise may have an important effect on the progression of Parkinson’s. A study published in the Cleveland Clinic Journal of Medicine in 2007 suggests that exercise may slow the progression of the disease and possibly even prevent it. Regular exercise may also reduce anxiety, increase confidence, offer more social interaction and provide a distraction from worries. It makes sense since exercise increases blood calcium levels which is known to increase dopamine production in the brain.

SottoPelle® has been working with PD patients for some time now. Many early-onset patients have seen benefits from using our bioidentical hormone pellet therapy. We have found that testosterone pellets decrease inflammation in the brain enabling men and women with Parkinson’s Disease to exercise. Estradiol pellets help restore dopamine production. This results in increased functionality and a slowed progression of their disease. Patients have also reported experiencing more mobility, diminished depression, and even a reduction in medications. SottoPelle® BHRT has additionally helped motivate them to exercise more, which in itself increases the vitality and energy needed to keep active. Improved quality of life seems to also be a common denominator among our PD patients.

For many years now, SottoPelle® has supported the mission to educate people on Parkinson’s and find a cure. Dr. Gino Tutera, our founder and director, presented an educational talk in 2015 to the Banner Neuro Center in Gilbert, AZ, to share his observations with the medical community. We have also participated in the annual Muhammad Ali Celebrity Fight Night for the past two years. This star-studded gala is known as one of the premiere charity events in the nation. For more than 20 years, celebrities have come together at this event to raise money for a variety of worthy causes, including the Muhammad Ali Parkinson Center at Barrow Neurological Institute in Phoenix. This year’s event is being held on April 9th at the JW Marriott Desert Ridge Resort & Spa in Phoenix, AZ, and we’ll be there supporting the cause. (

If you are living with Parkinson’s Disease, please give us a call. We would love to see if we can help you in your journey to a better quality life.

Bioidentical Hormone Replacement Therapy Can Help the Long Term Effects of Concussion

Traumatic brain injury (TBI) is a growing public health concern around the world. According to the CDC, concussion is the most commonly diagnosed TBI in the U.S. It estimates that 1.6 to 3.8 million sports and recreation related concussions occur in our country each year. Bicycling, football, hockey, soccer, boxing, basketball, track, gymnastics, softball, baseball all rank high on the scale of concussion injuries.

On the other hand, concussion isn’t just a sports or recreational phenomenon. It can happen to anyone—old, young or in-between, active or sedentary. This type of brain damage can also occur as the result of a bomb blast, an accident, a simple fall or even being shaken. Anything that causes the brain to move inside the head can result in a concussion, whether by an indirect or a direct jolt or blow. The effects from this so-called minor form of TBI are usually temporary. Nonetheless, there is strong evidence that even mild or moderate concussion may alter brain function and produce memory and thinking problems for the long term.

The most common consequence of brain injury, however, is pituitary malfunction and subsequent hormone deficiency. Researchers have found that injury to the pituitary gland disrupts its ability to create or convey its hormones to receptors that exist throughout the brain and the rest of the body. Many studies conclude that the chronic symptoms of TBI, such as depression, anxiety, irritability, sleep disorders, pain and the learning and memory problems mentioned above, are identical to those of hormone deficiency. Scientists have, in fact, recommended hormone replacement therapy for concussion and other TBI patients who test deficient in key endocrine hormones.

SottoPelle® remains a leader in the treatment of those with TBI. NFL players like Jim McMahon, Paul Krause, Bobby Bell and many other SottoPelle® patients who suffer from the aftermath of brain injury have reported improved quality of life and relief from symptoms related to their hormone deficiencies.

Our unique method of BHRT uses low dose bioidentical hormones that bind to and communicate perfectly with appropriate receptors within the cells. When hormone deficiencies are restored to beneficial levels, as they are with SottoPelle® BHRT, significant progress can be made. Since TBI patients will need to be on hormone replacement therapy for the rest of their lives, it only makes sense to choose a therapy that supports health rather than putting it at further risk.

What Is The Right Hormone Dosage for My Body?

Your hormone dosage needs to be unique to your own individual needs. One size does not fit all. The right prescription for you may be too much or too little for someone else. That’s why the standardized doses of pharmaceutical hormone replacement drugs do not make any sense at all. Everyone’s body chemistry and metabolism are different. What makes your metabolic process unique is a combination of things – the health of your organs, systems and glands, your genetic makeup, the medications you take, foods and liquids you regularly ingest, your stress and activity levels, and the list goes on. How you personally metabolize hormones will make all the difference in which hormone replacement dosage will benefit you the most.Couple hikers in high mountains


How do you know what’s right for you?

Hormones need to exist in proper amounts so your body can work like it is supposed to. Hormonal balance is a delicate thing to achieve using BHRT. It requires a precision method that is customized to work specifically for you. Many physicians still use guesswork to prescribe standard doses of dangerous, side-effect laden synthetic hormones. Their experiment is based on eliminating symptoms. It has nothing to do with treating your overall hormone deficiency or supporting your long term health.

Where do I start?

What you really need is to see a practitioner who understands:
1) the vital part played the hormone delivery method
2) the importance of proper testing, correctly interpreting the results, and prescribing the right amounts of key hormones that are missing
3) that the hormones must be exact matches for human hormones (bioidentical) in order to do their work

Likewise, to restore hormone balance, the method must be one your body recognizes and can work with; is capable of delivering hormone directly into your blood stream 24/7 for months at a time; and is both safe and effective for the long term. In fact, the goal of beneficial BHRT should be to both eliminate your symptoms and restore your body to hormonal balance.

SottoPelle® BHRT

This is precisely what we do at SottoPelle®. Our SottoPelle® Method is scientifically based and precision executed to create hormonal balance around the clock for months at a time. Using our proprietary pellet implant method, we treat your individual hormone needs with custom-compounded, low dose, bioidentical estradiol and testosterone. This method is proven safe and effective and is the only method capable of responding to your body when it needs more hormone.
Call us today for a consultation and join the thousands of others who have said goodbye to hormone deficiency and regained their lives with SottoPelle® BHRT.